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Generic Actos (pioglitazone)

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Generic name:[act-t-o-klo]Drug class:

Medically reviewed by. Last updated on Apr 2023.

What is Actos?

Actos is a prescription drug approved by the U. S. Food and Drug Administration (FDA) for treating type 2 diabetes mellitus. It is used to treat type 2 diabetes in adults.

Actos is used in adults for the treatment of type 2 diabetes and in adults for the treatment of type 1 diabetes. Type 2 diabetes mellitus is a condition in which the body does not produce enough insulin. Type 2 diabetes is caused by insulin resistance in the pancreas, or the inability of the pancreas to make insulin. Type 2 diabetes mellitus can be caused by a variety of factors including certain conditions such as certain heart disease, high blood pressure, and diabetes.

Actos is used to treat type 2 diabetes mellitus in adults. The drug is also used to treat symptoms of type 1 diabetes mellitus such as rapid weight loss, shortness of breath, and swelling of the ankles, feet, or legs.

How does Actos work?

Actos is a type of insulin that works to reduce sugar levels in the blood.

Actos is available in strengths of 45 mg, 45 mg, and 60 mg. In addition to controlling insulin levels, the drug is also used to treat type 1 diabetes in adults. It is also used to treat symptoms of diabetes in adults.

Actos has been approved for use by the FDA for the treatment of type 2 diabetes mellitus.

What are the benefits of Actos?

Actos is a prescription drug and may have some benefits for some people, particularly those who cannot take other diabetes drugs. However, it is not for everyone.

The drug may have several benefits. For one, it may help improve blood sugar control and reduce the need for exercise. Additionally, it may reduce the risk of diabetes-related complications such as type 2 diabetes and heart disease, such as heart disease and stroke. This may improve the quality of life for patients.

Some people may also experience increased bone mineral density. These benefits may be beneficial for certain people, particularly those who cannot take other diabetes drugs. For this reason, people may have a lower risk of fractures, diabetes-related complications, and other health problems.

What are the potential risks of Actos?

The potential risks of taking Actos are similar to those for any other type of medication. However, the drug may have potential risks for some people, particularly those who cannot take other diabetes drugs.

For people who cannot take other diabetes drugs, it is important to discuss potential risks with a healthcare provider. This can help determine if Actos is right for you.

Patients with diabetes who are at an increased risk of fractures, diabetes-related complications, and other health problems should be monitored and managed closely. If you are having an increased risk of fractures, diabetes-related complications, or other health problems, seek emergency medical treatment immediately.

Patients with a history of certain conditions or who are taking other medications that may interact with Actos should inform their doctor if they are taking Actos and discuss the potential risks with them before starting treatment.

What are the side effects of Actos?

Actos may cause a range of side effects.

Pioglitazone is an antipsychotic drug. It is used in the treatment of schizophrenia, bipolar disorder, and manic or mixed episodes of bipolar disorder.

Read on to learn more about the mechanism of action of Actos, and how to use Actos to manage your symptoms safely and effectively.

What is Actos?

Actos is an insulin-sensitizing drug. It is used in the treatment of patients with type 2 diabetes to control blood sugar (blood sugar) when insulin cannot be used (sugar).

The active ingredient in Actos is pioglitazone hydrochloride, which is a type of medicine that works by lowering the amount of sugar (glucose) in the blood, thus lowering blood sugar.

Pioglitazone and Actos are both used for the treatment of schizophrenia. In schizophrenia, the medication is given to people who have not responded to a typical stimulant like amphetamine.

However, Actos is not FDA-approved for the treatment of bipolar disorder. It is approved for the treatment of manic or mixed episodes of bipolar disorder.

Learn more about Actos and its uses.

How Actos Works

Actos is a type of medicine called a thiazolidinedione (TZD). It is a derivative of pioglitazone, an inhibitor of the phosphodiesterase type 5 enzyme. This medicine helps regulate blood sugar levels and helps prevent muscle fatigue, muscle weakness, and muscle atrophy. This medicine is typically used to treat people with diabetes, high blood pressure, or heart disease.

Actos comes in tablet form and is usually taken once a day, with or without food.

Actos Dosage

The usual dosage of Actos is 30-80 mg in a single day (usually between 1 and 4 weeks). However, there are a few specific doses for children and adults. Your doctor may prescribe a higher dose, depending on your specific needs.

Actos Side Effects

As with any medicine, Actos may cause side effects. Common side effects include:

  • Dry mouth
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Increased urination
  • Decreased blood pressure
  • Abdominal pain

Contact your doctor immediately if any of these side effects worsen or last more than a few days.

Rare side effects of Actos include:

  • Low blood pressure
  • Hypotension (high blood pressure)
  • Hearing impairment
  • Swelling of feet

If you notice any other side effects that you think are likely, contact your doctor immediately.

Actos Contraindications

People with a history of heart attack or stroke should not use Actos, as it may worsen the heart disease risk.

People with a history of kidney problems should avoid Actos as it may worsen the kidney problems.

Actos Risks

Actos is a dangerous drug. It has the potential to cause:

  • Loss of bone mineral density (BMD)
  • Kidney damage
  • Liver damage
  • Heart problems
  • Seizures
  • Allergic reactions

The risk of BMD loss is increased in people who take Actos. The risk may be higher in people with a history of heart disease, high blood pressure, diabetes, or other heart problems.

Actos Drug Interactions

Actos can interact with certain medications, including:

  • Anticoagulants like warfarin
  • Diuretics
  • Antipsychotics like olanzapine and risperidone
  • Thiazolidinediones like hydrochlorothiazide

This may cause your body to slow down, which can reduce your blood sugar. You may not feel better or feel better as your body adjusts.

Consuming alcohol with Actos can also cause severe reactions.

Market Overview

AstraZeneca’s (AZN) blockbuster Actos franchise was valued at approximately $9 billion in the U. S. in 2023, generating substantial revenue growth. Actos stands as a highly successful, widely used diabetes medication that revolutionizes the treatment of diabetes by helping individuals lose weight.

Market Scope

The Actos franchise is defined as a company that has generated annual sales of approximately $11 billion.

Indications and Usage

This market is segmented into diabetic, hypertension, and obesity management.

Diabetes Management

AstraZeneca’s diabetes management is a combination of blood sugar and insulin levels, along with weight loss medication. Its primary indication for diabetes management is controlling type 2 diabetes. This includes managing type 1 and type 2 diabetes-induced complications. Additionally, patients with type 1 or type 2 diabetes can gain weight with medication management.

Hypertension Management

AstraZeneca’s hypertension management is a combination of blood sugar and insulin levels, along with weight loss medication. Its primary indication for hypertension management is controlling hypertension.

Key Insights from AZN

Market Trends

This diabetes management segment includes diabetes, non-diabetic, weight management, and obesity management. With diabetes, approximately 80-85 percent of the nation’s population is prediabetic. This percentage increases to approximately 70 percent of adults with type 1 diabetes as a result of insulin resistance, hypoglycemia, and metabolic syndrome. Obesity management includes dietary changes, exercise, and a combination of dietary modifications, including a balanced diet and regular exercise.

Revenue Growth

AZN’s 2023 Actos franchise revenue increased to $9 billion in 2023 and continued to grow at a CAGR of 6.3% during the period. This growth is driven by the medication’s significant revenue growth, along with diabetes management’s significant impact on patient care.

Market Drivers

The rising prevalence of diabetes mellitus in the U. is a significant driver of the Actos franchise. As awareness of this condition continues to increase, the Actos franchise has fueled the demand for effective diabetes medications.

Regional Analysis

North America is also a significant region. The Actos franchise in this region is primarily driven by North America and Europe. The U. S., Australia, and New Zealand account for around 20 percent of this market.

North America

North America dominates the Actos franchise in the U. with annual sales of approximately $2.4 billion. This growth is attributed to the rising prevalence of diabetes, particularly in the U. and Canada.

Asia-Pacific

This region’s Actos franchise is driven by the growing incidence of diabetes in Asia-Pacific countries. The Asia-Pacific region accounts for approximately 20 percent of the Actos franchise in the U. S., with the prevalence of diabetes increasing with rising urbanization and advancements in healthcare.

Europe

Europe also dominates the Actos franchise in the U. with annual sales of approximately $3.9 billion. This growth is attributed to the increasing prevalence of diabetes in Europe and the region’s aging population.

Market Opportunities

The Actos franchise presents several opportunities for growth. By improving patients’ access to diabetes medication, AZN aims to mitigate these risks. Its success in reducing diabetes-related complications highlights the potential for growth.

Challenges and Restraints

AZN faces challenges that threaten its market growth. Its diabetes management franchise is subject to constrained clinical studies and regulatory approval. The regulatory approval process in North America faces challenges that could disrupt its market performance.

Competitive Landscape

The competitive landscape of the Actos franchise has been a significant factor in increasing the market size and revenue. AZN’s diabetes management franchise presents a promising avenue for growth.

Key Takeaways

  • The Actos franchise generated $9.3 billion in 2023 and is projected to be worth $11.2 billion in 2023.
  • The Actos franchise grew at a CAGR of 6.3% during the period.

The cost of Actos and other generic drugs may vary depending on your insurance plan and the pharmacy you visit. The average retail price for Actos is $18.42 per month, compared to $13.62 for the same drug in the United States.

Generic versions of the drug may not be covered by your insurance plan, but paying cash for them may help cover the cost of the drug. The cost of Actos may vary depending on your location and whether you are using insurance or paying cash for them.

Actos Prices at Your Pharmacy

If you are using insurance or paying cash for Actos, the price of Actos may vary based on the dosage and the pharmacy you visit. Generic versions of Actos are available through your local pharmacy, and you can buy them at the lower price of $5.99 per month in the United States.

The cost of Actos may vary depending on the dosage you take. You may find that the cost for Actos is significantly lower than the generic version. In general, the average retail price of Actos for a 12-month supply is $16.22 for a one-month supply, depending on the dosage.

Actos Prices in the United States

Actos (pioglitazone) is a medication used to treat type 2 diabetes. It is also sometimes prescribed to treat high blood sugar levels (glucose) in people with diabetes.

If you are using insurance, the cost of Actos may be lower than the generic version. Generic versions of Actos are available through your local pharmacy, but you can buy them at the lower cost of $2.50 per month in the United States.

The price of Actos varies depending on the dosage and whether it is used in combination with other diabetes medications. If you are using insurance or paying cash for Actos, the price of Actos may be lower than the cost of the generic version.

Actos Price in the United States

Generic Actos is a prescription medication used to treat type 2 diabetes. It is available as a tablet or extended-release tablet that you can take with or without food. You can take Actos with or without food, but it is important to take the medication at the same time each day for optimal absorption.

To find out which Actos dosage is best for you, talk with your doctor or pharmacist about using Actos to treat your diabetes. Actos is also sometimes used to treat high blood sugar levels (glucose) in people with type 2 diabetes.

If you are using insurance or paying cash for Actos, the price of Actos may be higher than the cost of the generic version.

People with type 2 diabetes may be prescribed Actos to treat the condition.

The price of Actos may vary depending on the dosage and whether it is used in combination with other diabetes medications.

If you are using insurance, the cost of Actos may be lower than the cost of the generic version. Generic versions of Actos are available through your local pharmacy, but you can buy them at the lower cost of $2.